论文
截至2023年5月,以通讯/第一作者在Sci Adv、Signal Transduct Target Ther、Adv Mater等发表论文70余篇,IF>10论文近40篇;共发表论文100余篇,撰写10余部专著章节,申请26件专利。
近期代表性论文:
1.Hu B, Li B, Li K, Liu Y, Li C, Zheng L, Zhang M, Yang T, Guo S, Dong X, Zhang T, Liu Q, Hussain A, Weng Y, Peng L, Zhao Y, Liang XJ, Huang Y*. Thermostable ionizable lipid-like nanoparticle (iLAND) for RNAi treatment of hyperlipidemia. Sci Adv. 2022 Feb 18;8(7):eabm1418. (ESI 1%) (IF= 14.957, 中科院1区)
2.Lu M#, Xing H#, Shao W, Zhang T, Zhang M, Wang Y, Li F, Weng Y, Zheng A, Huang Y*, Liang X-J*. Photo-activatable Silencing Extracellular Vesicle (PASEV) Sensitizes Cancer Immunotherapy. Adv Mater. 2022 Sep;34(35):e2204765. (IF= 32.086, 中科院1区)
3.Yang G, Li Z, Mohammed I, Zhao L, Wei W, Xiao H, Guo W, Zhao Y, Qu F, Huang Y*. Identification of SARS-CoV-2-against aptamer with high neutralization activity by blocking the RBD domain of spike protein 1. Signal Transduct Target Ther. 2021. 6(1): 1-4. (IF= 38.104, 中科院1区)
4.Huang Y*, Zheng S, Guo Z, de Mollerat du Jeu X, Liang XJ, Yang Z, Zhang HY, Gao S, Liang Z*. Ionizable liposomal siRNA therapeutics enables potent and persistent treatment of Hepatitis B. Signal Transduct Target Ther. 2022 Feb 11;7(1):38. (IF= 38.104, 中科院1区)
5.Zhang M, Shao W, Yang T, Liu H, Guo S, Zhao D, Weng Y, Liang X-J, Huang Y*. Conscription of Immune Cells by Light-Activatable Silencing NK-Derived Exosome (LASNEO) for Synergetic Tumor Eradication. Adv Sci (Weinh). 2022 Aug;9(22):e2201135. (IF= 17.521, 中科院1区)
6.Lu M#, Xing H#, Zheng A, Huang Y*, Liang XJ*. Overcoming Pharmaceutical Bottlenecks for Nucleic Acid Drug Development. Acc Chem Res. 2023 Feb 7;56(3):224-236. (IF= 24.466, 中科院1区)
7.Zhang M, Hussain A*, Yang H, Zhang J, Liang X-J, Huang Y*. mRNA-based modalities for infectious disease management. Nano Res. 2023; 16(1): 672-691. (IF= 10.269, 中科院1区)
8.Zhang M, Huang Y*. siRNA modification and delivery for drug development. Trends Mol Med. 2022 Oct;28(10):892-893. (IF= 15.272, 中科院1区)
9.Zhang T#, Guo S#, Li F*, Lan X, Jia Y, Zhang J, Huang Y*, Liang X-J*. Imaging-guided/improved diseases management for immune-strategies and beyond. Adv Drug Deliv Rev. 2022 Sep;188:114446. (IF= 17.873, 中科院1区)
10.Hussain A, Yang H, Zhang M, Liu Q*, Alotaibi G, Irfan M, He H, Chang J, Liang XJ, Weng Y, Huang Y*. mRNA vaccines for COVID-19 and diverse diseases. J Control Release. 2022 Mar 21;345:314-333. (ESI 1%) (IF= 11.467, 中科院1区)
11.Li C#, Yang T#, Weng Y#, Zhang M, Zhao D, Guo S, Hu B, Shao W, Wang X, Hussain A, Liang X, Huang Y*. Ionizable lipid-assisted efficient hepatic delivery of gene editing elements for oncotherapy. Bioact Mater. 2022 Jun 25;9:590-601. (ESI 1%) (IF= 16.874, 中科院1区)
12.Li C, Zhou J, Wu Y, Dong Y, Du L, Yang T, Wang Y, Guo S, Zhang M, Hussain A, Xiao H, Weng Y, Huang Y, Wang X, Liang Z, Cao H, Zhao Y, Liang X, Dong A, Huang Y*. Core Role of Hydrophobic Core of Polymeric Nanomicelle in Endosomal Escape of siRNA. Nano Lett. 2021 Feb 17. 21(8): 3680–3689. (IF= 12.262, 中科院1区)
13.Yang T#, Huang D#, Li C, Zhao D, Li J, Zhang M, Chen Y, Wang Q, Liang Z, Liang X, Li Z*, Huang Y*. Rolling microneedle electrode array (RoMEA) empowered nucleic acid delivery and cancer immunotherapy. Nano Today. 2021 Nov 2. 36:10101. (IF= 18.962, 中科院1区)
14.Yang T#, Li C#, Wang X#, Zhao D, Zhang M, Cao H, Liang Z, Xiao H, Liang X, Weng Y*, Huang Y*. Efficient hepatic delivery and protein expression enabled by optimized mRNA and ionizable lipid nanoparticle. Bioact Mater. 2020, 5 (4): 1053-1061. (IF= 16.874, 中科院1区)
15.Liu H, Huang L, Mao M, Ding J, Wu G, Fan W, Yang T, Zhang M, Huang Y*, Xie H-Y*. Viral Protein‐Pseudotyped and siRNA‐Electroporated Extracellular Vesicles for Cancer Immunotherapy. Adv Funct Mater. 2020: 2006515. (IF= 19.924, 中科院1区)
16.Hu B#, Zhong L#, Weng Y, Peng L, Huang Y*, Zhao Y*, Liang XJ*. Therapeutic siRNA: state of the art. Signal Transduct Target Ther. 2020 Jun 19;5(1):101. (ESI 1%) (IF= 38.104, 中科院1区)
17.Lu M, Huang Y*. Bioinspired exosome-like therapeutics and delivery nanoplatforms. Biomaterials. 2020 Mar 2;242: 119925. (ESI 1%) (IF= 15.304, 中科院1区)
18.Weng Y, Li C, Yang T, Hu B, Zhang M, Guo S, Xiao H, Liang XJ, Huang Y*. The challenge and prospect of mRNA therapeutics landscape. Biotechnol Adv. 2020 May-Jun;40:107534. (ESI 1%) (IF= 17.681, 中科院1区)
Weng Y, Xiao H, Zhang J, Liang XJ, Huang Y*. RNAi therapeutic and its innovative biotechnological evolution. Biotechnol Adv. 2019 Sep - Oct;37(5):801-825. (ESI 1%) (IF= 17.681, 中科院1区)
著作
1.Li C, Weng Y, Dong A, Liang X-J*, Huang Y*. Chapter 9 - Preparation and Evaluation of Rationally Designed Polymers for Efficient Endosomal Escape of siRNA. In: H. Tian and X. Chen (eds.), Gene Delivery, Biomaterial Engineering. 2021: 181-197. https://doi.org/10.1007/978-981-33-6198-0_4-1
2.Hussain A, Weng Y, Huang Y*. Chapter 9 - Graphene and graphene-based nanomaterials current applications and future perspectives. In: Shahzad, Rizvi, Yousaf, and Hussain. (eds) Drug Delivery using Nanomaterials. 2021, 209-228.
3.Dong Z#, Yang T#, Wu H, Brooks J. Yang R*, Huang Y*, Chang L*. Chapter 5 - Advanced microfluidic devices for cell electroporation and manipulation. In: Liu X, Sun Y. (eds) Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms. 2021, 105-123.
4.Yang G, Huang Y*. Aptamers for Targeted Therapy. In: Dong Y. (eds) Chapter 6 - Aptamers for Medical Applications. Springer, Singapore. 2021, 129-178.
5.Lu M#, Zhang M#, Hu Bo, Huang Y*. Chapter 6 - siRNA Design and GalNAc-Empowered Hepatic Targeted Delivery. In: Henrik J. Ditzel et al. (eds.) Design and Delivery of siRNA Therapeutics, Methods in Molecular Biology. Springer, Singapore. 2021, 77-100.
6.Huang D, Huang Y, Li Z*. Chapter 11 - Transdermal Delivery of Nucleic Acid Mediated by Punching and Electroporation. In: Li S., Chang L., Teissie J. (eds) Electroporation Protocols. Methods in Molecular Biology. Humana, New York, 2020, 101-112.
7.Weng Y, Huang Y*. Chapter 7 - The Advances of Biomacromolecule-based Nanomedicine in Brain Disease. In: Xue X. (eds) Nanomedicine in Brain Diseases. Springer, Singapore. 2019, 181-208.
8.黄渊余*,谭信.基因与遗传.马宏.生命科学原理与技术.北京:科学出版社.2019,第五章,97-140.(Huang Y*. Tan X. Chapter 5 - Gene and Genetics. In: Ma H. (eds) Principle and Technologies of Life Science. Science Press. 2020, 97-151)